Contents of this Article
Abstract and Physical Entities
As you may have noticed on the Materials Registry, a material is linked to a theoretical entry on TeselaGen’s system (i.e. a DNA material can be linked to a DNA sequence or DNA Part), but, what’s the difference between a material and a sample? You can think of a Material as the somewhat abstract idea of a biological entity, while the sample is the physical thing that exists. The general hierarchy of entries must be summarized as follows:
Next, let’s briefly explain each type of entry available on your Inventory Management System, their uses, and specific information on each one of them.
🚨 NOTE: The Registry Toolkit (found in the side panel as Molecules) stores your theoretical entities. Don't confuse it with the Materials Registry, part of the Materials and Inventory Management Toolkit, that stores physical materials.
What is the Registry Toolkit for?
The Registry Toolkit is found on the left side panel, on the submenu "Molecules".
Each type of molecule is shown on the typical library view. The type of molecules you can register are:
DNA, RNA, and Amino Acid Sequences: Any sequence can be stored in its corresponding library. They can be linked to materials or within each other.
Sequence Features: Annotations on a DNA region that indicates a structural or functional feature. Once you register a feature on your library, you can later use it to auto-annotate new sequences. To learn more about features click here.
DNA Parts, RNA Parts, Amino Acid Parts, and DNA Part Sets: A DNA/RNA part is a sequence identified as a functional DNA piece used to create designs that will be assembled. All Parts are Sequences, but not all your sequences will be parts. Part sets are groups of parts that are uploaded together (for example, because they share a common source or function).
Coding Sequences: These molecules link a source DNA Sequence to an Amino Acid Sequence and, optionally, a DNA Material.
Oligos: You can register DNA or RNA oligos.
Guide RNA Sequences: The gRNA library includes information about the spacer, scaffold sequences, and the linked Cas enzyme.
Region Annotations: Annotations on an Amino Acid sequence.
Functional Protein Units: One or more amino acid sequences grouped to perform a specific function (for example, a protein complex).
Cas Enzymes: Several Cas enzymes can be registered indicating their scaffold and PAM sequences, to be used in your CRISPR designs.
Tags: Tags and sub-tags are used to organize and categorize your data. They can be filtered to quickly find all data. To learn more about how tags and other TeselaGen features can be used to organize your data, click here.
Import Collections: An import collection is a grouping of entities that were uploaded together. Any time you upload data in bulk, a new Import Collection will be created.